Information for patients with takayasu s arteritis. Takayasu arteritis has been associated with different human leucocyte antigen hla alleles in different populations. Objectives takayasu arteritis is a chronic inflammatory obliterative disease of the great vessels that mainly affects the aorta and its primary branches. Learn how health care professionals diagnosis takayasu arteritis by examining blood work. Abstract we describe the case of a 28yearold woman who presented to our clinic with a history of chronic bilateral visual loss and recent episodes of syncope. Takayasu arteritis is a type of arteritis that causes inflammation of the large and mediumsized arteries, which further leads to aneurysms, stenoses, and fibrosis of the affected artery. Clinical features and diagnoses of takayasu arteritis. Shelhamer jh, volkman dj, parrillo je, lawley tj, johnston mr, fauci as. In its early phase, the clinical presentation and laboratory tests are nonspecific, so accurate diagnosis frequently depends on imaging studies. Vasculitis is uncommon, and large or median vessel vasculitis, such as takayasu and temporal arteritis, are even more. Pentraxin3 as a marker of disease activity in takayasu arteritis. Takayasu arteritis is a rare, systemic, inflammatory largevessel vasculitis of unknown etiology that most commonly affects women of.
Isolated ta of pulmonary artery branches is very rare. The american college of rheumatology 1990 criteria for the classification of takayasu arteritis. Takayasu arteritis ta is a rare disease affecting chiefly young women, although it can affect both men and women and persons of many different ethnicities. Incidence in the usa and europe ranges from 1 to 3. Patients with takayasu arteritis can have symptoms like weak or absent pulses in extremities, widely varying blood pressures, and dizziness.
Takayasu s arteritis is a chronic systematic inflammatory disease. The first case corresponds to a young woman who met the american college of rheuma tology criteria for takayasu arteritis. Takayasu arteritis also known as the pulseless disease is a type of vasculitis that affects large arteries and leads to significant narrowing of the vasculature. Takayasu arteritis tak is a rare inflammatory largevessel vasculitis primarily affecting the aorta and its major branches, but also other large. Ta carries a high morbidity rate, but importantly, overall mortality has declined over time such that the 15year survival rate has increased from 82. Arend wp1, michel ba, bloch da, hunder gg, calabrese lh, edworthy sm. The symptomatology elicited is dependent on the precise vessel affected, and in the majority of the cases, focal symptoms are experienced indicating an abnormally low perfusion of the affected organ or extremity. Takayasu arteritis ta is a chronic inflammatory condition of unknown cause that involves large and medium caliber arteries, including the aorta and its main branches, and the coronary and pulmonary arteries. Takayasu arteritis ta, also known as idiopathic medial aortopathy or pulseless disease, is a granulomatous large vessel vasculitis that predominantly affects. Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main branches and it constitutes one of the more common vasculitides in children.
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